Disable USB ports on Windows PC via Registry

1. Click on Start.
2. Click on Run. If you cannot find RUN, type it in the search box.
3. Type "regedit" without quotes. This will launch the Registry Editor.
4. Navigate to  HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\usbstor.
5. In the work area, double click on Start.
6. In the Value Data box, enter 4.
7. Click on OK.
8. Close Registry Editor and refresh your desktop.
9. To re-enable access to your USB ports, enter 3 in the Value Data box in Step 6.

Try it in your Risk.